This Original Mississippi Pot Roast cooked in the slow cooker is a tender, flavorful roast seasoned with salt, pepper, pepperoncini peppers, and a zesty combination of ranch and beefy onion soup mixes for a dinner entree that will have everyone’s mouths watering.

This Mississippi Chuck Roast is one of the most flavorful slow cooker dishes that I’ve ever had. You may be wondering why it’s called a “Mississippi” Chuck Roast? That’s because someone in Mississippi came up with a similar recipe, and it just stuck. What makes it different from a regular chuck roast is the amazing, zesty combination of flavors.
All that you have to do to make this pot roast is put everything into the slow cooker. How easy is that? Just brown your meat, add it into the slow cooker, put your seasonings into the slow cooker, and voila! When it is ready, the meat becomes so tender that it falls apart when shredded with two forks. It is tender, juicy, delicious, and will absolutely melt in your mouth!
Why You’ll Love This Mississippi Pot Roast Recipe
- It requires almost no work to make this pot roast.
- You only need a few ingredients to make this roast.
- It makes a slow cooker full of meat, making this a great option for large families or gatherings.
- This roast is packed with flavor and is very tender.
- It is a very easy meal to make on a weeknight.
- It is so tasty that everyone will ask for seconds (and thirds)!
Equipment Needed To Make This Simple Mississippi Pot Roast Slow Cooker
- Large Skillet
- Slow Cooker
- Two Forks
Ingredients For Your Original Mississippi Roast Recipe
- Chuck Roast
- Olive Oil
- Salt & Black Pepper
- Pepperoncini Peppers
- Butter
- Ranch Seasoning
- Beefy Onion Soup Mix
How To Make Original Mississippi Chuck Roast
- Sprinkle salt and pepper over both sides of the chuck roast and set aside.
- In a large skillet over medium-high heat. Add olive oil and coat the skillet evenly. Add roast to the skillet and sear all sides for 1-2 minutes including the sides and ends.
- Remove roast from skillet and add to slow cooker.
- Pour ranch dressing mix and beefy onion soup over the top. Then place the stick of butter and pepperoncini peppers on top of the roast.
- Cover and on high for 3-4 hours and on low for 7-8 hours.
- Once the roast is fully cooked. Shred with two forks and remove the large pieces of fat.

What to Serve/Pair with Your Original Mississippi Roast Recipe
One of my favorite sides to pair with a roast is potatoes. These light and fluffy Mashed Potatoes are the perfect pairing. You can even pour a little juice from the slow cooker on top, similar to a gravy - yum! You can also try these tasty Slow Cooker Baked Potatoes.
For a veggie to go with this Mississippi Pot Roast, I like to make these Garlic and Bacon Green Beans. They add a little bit of sweetness to the meal and have just the right flavors to pair well with the roast.
For dessert, just about anything will pair well with this roast, but if you want to turn it into a true comfort meal, this Homemade Apple Pie will do the trick. Serve it with a scoop of vanilla ice cream for a special treat.
Popular Substitutions & Additions
If you want more of an onion flavor, add in a few chopped onions to the slow cooker. They’ll be tasty to eat along with the roast, especially after cooking in the flavorful juice all day.
How To Reheat & Store Mississippi Pot Roast
This roast is just as tasty when it is leftover. If you have any left, transfer it to a sealed container and stick it in the fridge. It will last for up to 2 days. To reheat individual portions, heat them in the microwave for 2 minutes, or until warm.
You can also freeze this roast! Once it has completely cooled, transfer it to a sealed, freezer-safe container and put it in the freezer. It will last for up to 8 weeks. When you are ready to cook it, thaw it completely in the fridge, then heat it on low or high, depending on how soon you want it to be ready, in the slow cooker until it is warm.
FAQs
Yes, I always recommend doing this so that nothing will stick, and it makes it much easier to clean up!
Nope, you can use whichever brands of seasoning mix that you prefer. You can even try making your own!
When your roast is fully cooked, it will shred very easily with two forks.

Other Slow Cooker Recipe Recipes You’ll Love
- Easy, Cheesy Slow Cooker Scalloped Potatoes
- Slow Cooker Chicken Casserole (With Ritz Crackers)
- Crock Pot Lazy Lasagna with Ravioli
- Slow Cooker Cheesy Ranch Potatoes (With Bacon)
- Slow Cooker Ham with Pineapple & Brown Sugar
Don’t Forget To Come Back And Let Me Know How Your Mississippi Pot Roast Turned Out!

Mississippi Pot Roast
Equipment
Ingredients
- 3 lb chuck roast
- 2 tbsp olive oil
- 1 tsp salt
- 1½ tsp black pepper
- 6 pepperoncini peppers
- ½ cup unsalted butter
- 1 packet ranch dressing mix
- 1 packet beefy onion soup mix
Instructions
- Sprinkle salt and pepper over both sides of the chuck roast and set aside.
- In a large skillet over medium-high heat. Add olive oil and coat the skillet evenly. Add roast to the skillet and sear all sides for 1-2 minutes including the sides and ends.
- Remove roast from skillet and add to slow cooker.
- Pour ranch dressing mix and beefy onion soup over the top. Then place the stick of butter and pepperoncini peppers on top of the roast.
- Cover and on high for 3-4 hours and on low for 7-8 hours.
- Once the roast is fully cooked. Shred with two forks and remove the large pieces of fat.
Nutrition
*All nutrition information provided is automatically calculated and is an estimate and will vary based on ingredients, brands, and changes in cooking methods listed in the recipe. If you need exact numbers on your ingredients, I would recommend calculating them with your prefered nutrition calculator.
Katherine Nichols
This beef recipe is amazing!! Tender buttery within the juices..I have made this recipe several times and no left overs! Simply delicious
Ryan Allen
So glad you liked it! It is one of my family's favorites.